Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
gptkb:drug |
| gptkbp:approvedBy |
gptkb:Japan
|
| gptkbp:ATCCode |
L01XX45
|
| gptkbp:CASNumber |
162652-95-1
|
| gptkbp:category |
gptkb:vitamin_A
antineoplastic agent |
| gptkbp:chemicalFormula |
C24H25NO2
|
| gptkbp:developedBy |
gptkb:Japan
|
| gptkbp:hasSMILES |
CC1(C)C2=C(C(C1(C)C)=O)C=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O
|
| https://www.w3.org/2000/01/rdf-schema#label |
tamibarotene
|
| gptkbp:IUPACName |
4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid
|
| gptkbp:KEGGID |
D07441
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
retinoic acid receptor agonist
|
| gptkbp:molecularWeight |
359.46 g/mol
|
| gptkbp:PubChem_CID |
5311107
CHEMBL2103832 DB11637 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
headache
rash elevated liver enzymes dry skin |
| gptkbp:synonym |
Am80
4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid |
| gptkbp:target |
retinoic acid receptor alpha
retinoic acid receptor beta |
| gptkbp:UNII |
1Y8V5V1I8A
|
| gptkbp:usedFor |
gptkb:acute_promyelocytic_leukemia
|
| gptkbp:bfsParent |
gptkb:RARA
|
| gptkbp:bfsLayer |
7
|