Statements (30)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:drug
                                        
                                         gptkb:antimalarial_medication  | 
                            
| gptkbp:activeIngredient | 
                                    
                                        
                                            gptkb:tafenoquine
                                        
                                         | 
                            
| gptkbp:approvalYear | 
                                    
                                        
                                            
                                            2018
                                        
                                        
                                         | 
                            
| gptkbp:approvedBy | 
                                    
                                        
                                            gptkb:FDA
                                        
                                         gptkb:TGA  | 
                            
| gptkbp:ATCCode | 
                                    
                                        
                                            
                                            P01BA15
                                        
                                        
                                         | 
                            
| gptkbp:brand | 
                                    
                                        
                                            
                                            Kozenis
                                        
                                        
                                         | 
                            
| gptkbp:CASNumber | 
                                    
                                        
                                            
                                            106635-80-7
                                        
                                        
                                         | 
                            
| gptkbp:chemicalFormula | 
                                    
                                        
                                            
                                            C24H28F3N3O3
                                        
                                        
                                         | 
                            
| gptkbp:contraindication | 
                                    
                                        
                                            gptkb:G6PD_deficiency
                                        
                                         | 
                            
| gptkbp:developer | 
                                    
                                        
                                            gptkb:Medicines_for_Malaria_Venture
                                        
                                         GlaxoSmithKline  | 
                            
| gptkbp:eliminationHalfLife | 
                                    
                                        
                                            
                                            ~15 days
                                        
                                        
                                         | 
                            
| gptkbp:legalStatus | 
                                    
                                        
                                            
                                            prescription only
                                        
                                        
                                         | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            
                                            8-aminoquinoline derivative
                                        
                                        
                                         disrupts Plasmodium mitochondrial function  | 
                            
| gptkbp:pregnancyCategory | 
                                    
                                        
                                            
                                            not recommended
                                        
                                        
                                         | 
                            
| gptkbp:relatedTo | 
                                    
                                        
                                            gptkb:primaquine
                                        
                                         | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            oral
                                        
                                        
                                         | 
                            
| gptkbp:sideEffect | 
                                    
                                        
                                            gptkb:anemia
                                        
                                         nausea vomiting dizziness headache  | 
                            
| gptkbp:usedFor | 
                                    
                                        
                                            
                                            malaria
                                        
                                        
                                         Plasmodium vivax malaria  | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:Medicines_for_Malaria_Venture
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            7
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            tafenoquine (Kozenis)
                                        
                                        
                                         |