|
gptkbp:instanceOf
|
gptkb:drug
antiviral drug
|
|
gptkbp:approvedBy
|
gptkb:FDA
1952
|
|
gptkbp:ATCCode
|
P01BA03
|
|
gptkbp:brand
|
Primaquine Phosphate
|
|
gptkbp:CASNumber
|
90-34-6
|
|
gptkbp:chemicalFormula
|
C15H21N3O
|
|
gptkbp:contraindication
|
gptkb:G6PD_deficiency
pregnancy
|
|
gptkbp:discoveredBy
|
gptkb:United_States_Army
|
|
gptkbp:drugClass
|
8-aminoquinoline
|
|
gptkbp:eliminationHalfLife
|
4-7 hours
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
primaquine
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
disrupts mitochondrial electron transport in parasites
|
|
gptkbp:MeSH_ID
|
D011323
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
4908
|
|
gptkbp:riskFactor
|
hemolysis in G6PD-deficient patients
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
gptkb:anemia
gptkb:methemoglobinemia
|
|
gptkbp:UNII
|
gptkb:6M3C89ZY6R
|
|
gptkbp:usedFor
|
treatment of malaria
eradication of hypnozoites
prevention of malaria relapse
treatment of Plasmodium falciparum gametocytes
treatment of Plasmodium ovale
treatment of Plasmodium vivax
|
|
gptkbp:bfsParent
|
gptkb:Plasmodium_ovale
gptkb:Plasmodium_vivax
|
|
gptkbp:bfsLayer
|
5
|