|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:bfsLayer
|
6
|
|
gptkbp:bfsParent
|
gptkb:Plasmodium_vivax
gptkb:Plasmodium_malariae
|
|
gptkbp:activities
|
inhibits mitochondrial electron transport
|
|
gptkbp:appointed_by
|
oral tablet
|
|
gptkbp:approves
|
gptkb:legislation
gptkb:United_States
|
|
gptkbp:availability
|
prescription only
over-the-counter in some countries
|
|
gptkbp:brand
|
Primaquine phosphate
|
|
gptkbp:clinical_trial
|
Phase II
Phase III
|
|
gptkbp:composed_of
|
gptkb:chemical_compound
extraction from natural sources
|
|
gptkbp:contraindication
|
G6 PD deficiency
|
|
gptkbp:developed_by
|
gptkb:US_Army
|
|
gptkbp:discovered_by
|
1940s
|
|
gptkbp:dissolved
|
soluble in water
soluble in alcohol
|
|
gptkbp:dosage_form
|
gptkb:tablet
suspension
|
|
gptkbp:duration
|
14 days
7 days
|
|
gptkbp:formulation
|
oral
|
|
gptkbp:historical_event
|
gptkb:World_War_II
post-exposure prophylaxis
treatment of relapsing malaria
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
primaquine
|
|
gptkbp:ingredients
|
C15 H18 N3 O
|
|
gptkbp:interacts_with
|
antibiotics
antidepressants
antimalarial drugs
|
|
gptkbp:invention
|
patented
generic available
|
|
gptkbp:is_used_for
|
treatment of malaria
prevention of malaria
|
|
gptkbp:lifespan
|
3 to 8 hours
|
|
gptkbp:manager
|
oral
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:provides_information_on
|
WHO recommendations
CDC guidelines
|
|
gptkbp:research_areas
|
pharmacology
infectious diseases
tropical medicine
malaria eradication
|
|
gptkbp:side_effect
|
dizziness
headache
nausea
allergic reactions
hemolytic anemia
methemoglobinemia
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:targets
|
gptkb:Plasmodium_falciparum
gptkb:Plasmodium_vivax
gptkb:Plasmodium_ovale
|