t(11;14)(q13;q32) translocation
GPTKB entity
Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chromosomal_band
|
| gptkbp:associatedWith |
gptkb:mantle_cell_lymphoma
multiple myeloma |
| gptkbp:breakpointLocation |
gptkb:11q13
14q32 |
| gptkbp:chromosomeInvolved |
gptkb:chromosome_14
chromosome 11 |
| gptkbp:detects |
gptkb:FISH
PCR karyotyping |
| gptkbp:involvedIn |
gptkb:CCND1
gptkb:IGH |
| gptkbp:mechanismOfAction |
juxtaposition of CCND1 and IGH
|
| gptkbp:result |
overexpression of cyclin D1
|
| gptkbp:significance |
diagnostic marker for mantle cell lymphoma
prognostic marker in multiple myeloma |
| gptkbp:bfsParent |
gptkb:mantle_cell_lymphoma
gptkb:Mantle_Cell_Lymphoma |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
t(11;14)(q13;q32) translocation
|