t(11;14)(q13;q32) translocation

GPTKB entity

Statements (20)
Predicate Object
gptkbp:instanceOf chromosomal band
gptkbp:associatedWith gptkb:mantle_cell_lymphoma
multiple myeloma
gptkbp:breakpointLocation gptkb:11q13
14q32
gptkbp:chromosomeInvolved gptkb:chromosome_14
chromosome 11
gptkbp:detects gptkb:FISH
PCR
karyotyping
https://www.w3.org/2000/01/rdf-schema#label t(11;14)(q13;q32) translocation
gptkbp:involvedIn gptkb:CCND1
gptkb:IGH
gptkbp:mechanismOfAction juxtaposition of CCND1 and IGH
gptkbp:result overexpression of cyclin D1
gptkbp:significance diagnostic marker for mantle cell lymphoma
prognostic marker in multiple myeloma
gptkbp:bfsParent gptkb:mantle_cell_lymphoma
gptkb:Mantle_Cell_Lymphoma
gptkbp:bfsLayer 7