semantic variant PPA

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf neurological disorder
primary progressive aphasia subtype
gptkbp:affects language function
gptkbp:alsoKnownAs gptkb:semantic_dementia
gptkb:svPPA
gptkbp:associatedWith anterior temporal lobe atrophy
frontotemporal lobar degeneration
gptkbp:cause abnormal protein accumulation (TDP-43, sometimes tau)
gptkbp:characterizedBy fluent but empty speech
impaired naming
impaired single-word comprehension
loss of word meaning
gptkbp:diagnosedBy neuropsychological testing
MRI brain imaging
gptkbp:differentialDiagnosis gptkb:Alzheimer's_disease
gptkb:logopenic_variant_PPA
gptkb:nonfluent/agrammatic_variant_PPA
gptkbp:firstDescribed 1992
https://www.w3.org/2000/01/rdf-schema#label semantic variant PPA
gptkbp:ICD-10_code G31.0
gptkbp:onset middle age
gptkbp:prevalence rare
gptkbp:progression gradual
gptkbp:symptom difficulty recognizing objects
difficulty understanding words
gptkbp:treatment supportive care
speech therapy
gptkbp:bfsParent gptkb:Frontotemporal_degeneration
gptkb:Frontotemporal_Dementia
gptkb:primary_progressive_aphasia
gptkbp:bfsLayer 6