svPPA

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf neurological disorder
syndrome
gptkbp:affects adults, typically 50-65 years old
gptkbp:associatedWith anterior temporal lobe atrophy
frontotemporal lobar degeneration
gptkbp:characterizedBy fluent but empty speech
impaired naming
loss of word meaning
gptkbp:commonPathology TDP-43 proteinopathy
gptkbp:diagnosedBy clinical assessment
neuroimaging
gptkbp:differentialDiagnosis gptkb:Alzheimer's_disease
gptkb:logopenic_variant_PPA
gptkb:nonfluent/agrammatic_variant_PPA
gptkbp:firstDescribed late 1990s
https://www.w3.org/2000/01/rdf-schema#label svPPA
gptkbp:isA primary progressive aphasia subtype
gptkbp:prevalence rare
gptkbp:progression gradual
gptkbp:riskFactor family history of neurodegenerative disease
gptkbp:standsFor semantic variant primary progressive aphasia
gptkbp:symptom impaired single-word comprehension
anomia
surface dyslexia
gptkbp:treatment supportive care
speech therapy
gptkbp:bfsParent gptkb:semantic_variant_PPA
gptkbp:bfsLayer 7