semantic dementia

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf neurodegenerative disease
syndrome
gptkbp:affects adults, typically age 50-65
anterior temporal lobes
gptkbp:associatedWith TDP-43 pathology
gptkbp:characterizedBy progressive language impairment
loss of semantic memory
gptkbp:diagnosedBy clinical assessment
MRI
neuropsychological testing
gptkbp:differentialDiagnosis gptkb:Alzheimer's_disease
gptkb:nonfluent/agrammatic_variant_PPA
logopenic progressive aphasia
gptkbp:firstDescribed 1989
Julie Snowden
gptkbp:frequency rare
https://www.w3.org/2000/01/rdf-schema#label semantic dementia
gptkbp:ICD-10_code G31.0
gptkbp:isA gptkb:primary_progressive_aphasia
frontotemporal lobar degeneration
gptkbp:languageImpairmentType fluent aphasia
gptkbp:MeSH_ID D020961
gptkbp:OMIM 600274
gptkbp:prognosis progressive and irreversible
gptkbp:progression gradual
gptkbp:symptom anomia
impaired object recognition
impaired word comprehension
surface dyslexia
gptkbp:treatment supportive care
speech therapy
gptkbp:bfsParent gptkb:Frontotemporal_dementia
gptkbp:bfsLayer 6