|
gptkbp:instanceOf
|
gptkb:syndrome
gptkb:neurodegenerative_disease
|
|
gptkbp:affects
|
adults, typically age 50-65
anterior temporal lobes
|
|
gptkbp:associatedWith
|
TDP-43 pathology
|
|
gptkbp:characterizedBy
|
progressive language impairment
loss of semantic memory
|
|
gptkbp:diagnosedBy
|
clinical assessment
MRI
neuropsychological testing
|
|
gptkbp:differentialDiagnosis
|
gptkb:Alzheimer's_disease
gptkb:nonfluent/agrammatic_variant_PPA
logopenic progressive aphasia
|
|
gptkbp:firstDescribed
|
1989
Julie Snowden
|
|
gptkbp:frequency
|
rare
|
|
gptkbp:ICD-10_code
|
G31.0
|
|
gptkbp:isA
|
gptkb:primary_progressive_aphasia
frontotemporal lobar degeneration
|
|
gptkbp:languageImpairmentType
|
fluent aphasia
|
|
gptkbp:MeSH_ID
|
D020961
|
|
gptkbp:OMIM
|
600274
|
|
gptkbp:prognosis
|
progressive and irreversible
|
|
gptkbp:progression
|
gradual
|
|
gptkbp:symptom
|
anomia
impaired object recognition
impaired word comprehension
surface dyslexia
|
|
gptkbp:treatment
|
supportive care
speech therapy
|
|
gptkbp:bfsParent
|
gptkb:semantic_variant_PPA
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
semantic dementia
|