Statements (55)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:psychologist
|
| gptkbp:affects |
younger adults
|
| gptkbp:associated_with |
gptkb:historical_event
anxiety apathy social withdrawal compulsive behaviors TDP-43 protein abnormalities loss of empathy tau protein abnormalities disinhibition memory loss (less common than in Alzheimer's) |
| gptkbp:caused_by |
neurodegeneration
|
| gptkbp:clinical_trial |
genetic studies
new therapies neuroimaging techniques symptom management |
| gptkbp:community_impact |
can be significant
can lead to caregiver burnout requires adjustments in family dynamics |
| https://www.w3.org/2000/01/rdf-schema#label |
Frontotemporal Dementia
|
| gptkbp:impact |
social relationships
employment caregivers |
| gptkbp:is_involved_in |
available for patients
available for caregivers |
| gptkbp:is_popular_in |
less common than Alzheimer's disease
|
| gptkbp:number_of_teams |
varies by individual
|
| gptkbp:premiered_on |
typically between ages 40 and 65
|
| gptkbp:public_awareness |
aim to educate public
aim to reduce stigma aim to promote research funding |
| gptkbp:research_focus |
biomarkers
genetic factors |
| gptkbp:risk_factor |
C9orf72 gene
GRN gene MAPT gene |
| gptkbp:social_responsibility |
clinical assessment
neuroimaging Language variant frontotemporal dementia criteria Neurocognitive Disorders Behavioral variant frontotemporal dementia criteria |
| gptkbp:supports |
can be costly
involves multidisciplinary approach may be necessary |
| gptkbp:symptoms |
behavioral changes
personality changes language difficulties |
| gptkbp:treatment |
supportive care
medications for symptoms |
| gptkbp:type |
behavioral variant
nonfluent variant semantic variant |
| gptkbp:bfsParent |
gptkb:C9orf72
|
| gptkbp:bfsLayer |
6
|