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gptkbp:instance_of
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gptkb:software
|
|
gptkbp:activities
|
HMG-Co A reductase inhibitor
|
|
gptkbp:approves
|
gptkb:2003
gptkb:FDA
|
|
gptkbp:brand
|
gptkb:Crestor
Ezallor
|
|
gptkbp:clinical_trial
|
various studies
|
|
gptkbp:contraindication
|
liver disease
pregnancy
|
|
gptkbp:counseling_services
|
take with or without food
do not crush or chew
report unexplained muscle pain
avoid grapefruit juice
|
|
gptkbp:developed_by
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gptkb:temple
|
|
gptkbp:dosage_form
|
gptkb:tablet
varies by condition
|
|
gptkbp:has_ability
|
10 mg
5 mg
20 mg
40 mg
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
rosuvastatin
|
|
gptkbp:ingredients
|
C22 H28 F N3 O6 S
|
|
gptkbp:interacts_with
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gptkb:cyclosporine
gptkb:warfarin
antacids
|
|
gptkbp:invention
|
gptkb:2023
|
|
gptkbp:is_monitored_by
|
liver function tests
renal function
lipid levels
|
|
gptkbp:is_used_for
|
lowering cholesterol
|
|
gptkbp:marketed_as
|
gptkb:legislation
gptkb:Australia
gptkb:Japan
gptkb:United_States
gptkb:Native_American_tribe
|
|
gptkbp:pharmacokinetics
|
excreted in urine
high bioavailability
oral administration
metabolized in liver
|
|
gptkbp:side_effect
|
headache
muscle pain
nausea
allergic reactions
constipation
liver enzyme elevation
gastrointestinal issues
diabetes risk
kidney effects
|
|
gptkbp:type_of
|
287714-41-4
|
|
gptkbp:bfsParent
|
gptkb:simvastatin
|
|
gptkbp:bfsLayer
|
5
|