ribonuclease H

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:CASNumber 9001-98-3
gptkbp:cofactor Mg2+
Mn2+
gptkbp:discoveredBy Hans-Albrecht Stein
Peter Hausen
gptkbp:discoveredIn 1969
gptkbp:EC_number 3.1.26.4
gptkbp:foundIn gptkb:Bacteria
viruses
archaea
eukaryotes
gptkbp:function cleaves RNA in RNA-DNA hybrids
gptkbp:gene_ontology_ID GO:0004523
gptkbp:hasIsoform RNase H1
RNase H2
https://www.w3.org/2000/01/rdf-schema#label ribonuclease H
gptkbp:involves DNA replication
retroviral replication
removal of RNA primers
gptkbp:product single-stranded DNA
nucleotides
gptkbp:substrate RNA-DNA hybrid
gptkbp:UniProtID P00798
gptkbp:used_in molecular biology research
cDNA synthesis
removal of RNA from RNA-DNA hybrids
gptkbp:bfsParent gptkb:RNAse_H
gptkbp:bfsLayer 7