Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:ribonuclease_H
|
| gptkbp:cofactor |
Mg2+
Mn2+ |
| gptkbp:discoveredBy |
1969
|
| gptkbp:EC_number |
3.1.26.4
|
| gptkbp:foundIn |
viruses
prokaryotes eukaryotes |
| gptkbp:function |
hydrolyzes RNA in RNA-DNA hybrids
|
| gptkbp:gene |
gptkb:RNASEH1
gptkb:RNASEH2A gptkb:RNASEH2B gptkb:RNASEH2C |
| https://www.w3.org/2000/01/rdf-schema#label |
RNAse H
|
| gptkbp:inhibitedBy |
RNase H inhibitors
|
| gptkbp:involves |
DNA replication
retroviral replication removal of RNA primers |
| gptkbp:product |
degraded RNA
intact DNA strand |
| gptkbp:relatedTo |
gptkb:DNA_polymerase_I
gptkb:HIV_reverse_transcriptase |
| gptkbp:structure |
contains RNase H domain
|
| gptkbp:substrate |
RNA-DNA hybrid
|
| gptkbp:used_in |
reverse transcription
molecular biology research antisense technology |
| gptkbp:bfsParent |
gptkb:Enzymes
|
| gptkbp:bfsLayer |
6
|