|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
produces D2S and D2L isoforms
|
|
gptkbp:associatedWith
|
motor control
reward pathways
behavioral responses to dopamine
|
|
gptkbp:encodes
|
D2 dopamine receptor
|
|
gptkbp:Entrez_Gene_ID
|
24318
ENSRNOG00000024651
|
|
gptkbp:expressedIn
|
gptkb:striatum
gptkb:pituitary_gland
brain
|
|
gptkbp:function
|
dopamine receptor activity
|
|
gptkbp:gene
|
Drd2
|
|
gptkbp:GO_term
|
GO:0004952
GO:0007186
GO:0007212
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
rat Drd2
|
|
gptkbp:involves
|
gptkb:cAMP_signaling_pathway
inhibition of adenylyl cyclase
|
|
gptkbp:locatedOnChromosome
|
chromosome 8
|
|
gptkbp:mutationAssociatedWith
|
affects drug addiction susceptibility
alters locomotor activity
|
|
gptkbp:organism
|
gptkb:Rattus_norvegicus
|
|
gptkbp:orthologIn
|
gptkb:mouse_Drd2
human DRD2
|
|
gptkbp:product
|
D2R
|
|
gptkbp:receptor_type
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:relatedTo
|
dopaminergic signaling
|
|
gptkbp:target
|
antipsychotic drugs
dopamine agonists
dopamine antagonists
|
|
gptkbp:UniProtID
|
P61169
|
|
gptkbp:bfsParent
|
gptkb:dopamine_receptor_D2
|
|
gptkbp:bfsLayer
|
7
|