Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:alsoKnownAs |
rapamycin analogs
|
| gptkbp:approvedBy |
organ transplantation
renal cell carcinoma |
| gptkbp:derivedFrom |
gptkb:rapamycin
|
| https://www.w3.org/2000/01/rdf-schema#label |
rapalogs
|
| gptkbp:includes |
gptkb:everolimus
gptkb:sirolimus gptkb:temsirolimus gptkb:ridaforolimus |
| gptkbp:mechanismOfAction |
mTOR inhibition
|
| gptkbp:notableExample |
gptkb:everolimus
gptkb:sirolimus gptkb:temsirolimus gptkb:ridaforolimus |
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
immunosuppression
rash hyperlipidemia mucositis |
| gptkbp:target |
gptkb:mTORC1
|
| gptkbp:usedFor |
gptkb:cancer
immunosuppression |
| gptkbp:bfsParent |
gptkb:mTOR_pathway
|
| gptkbp:bfsLayer |
5
|