Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
gptkb:pyruvate
gptkb:ADP Ca2+ |
| gptkbp:catalyzes |
conversion of pyruvate to acetyl-CoA
|
| gptkbp:cofactor |
gptkb:Coenzyme_A
gptkb:FAD NAD+ thiamine pyrophosphate lipoic acid |
| gptkbp:component |
gptkb:pyruvate_dehydrogenase_complex
|
| gptkbp:deficiencyCauses |
gptkb:pyruvate_dehydrogenase_deficiency
|
| gptkbp:EC_number |
1.2.4.1
|
| gptkbp:foundIn |
mitochondria
|
| gptkbp:gene |
gptkb:PDHA2
gptkb:PDHB gptkb:PDHA1 |
| https://www.w3.org/2000/01/rdf-schema#label |
pyruvate dehydrogenase
|
| gptkbp:inhibitedBy |
gptkb:NADH
acetyl-CoA |
| gptkbp:pathway |
aerobic respiration
glycolysis citric acid cycle |
| gptkbp:product |
gptkb:NADH
CO2 acetyl-CoA |
| gptkbp:regulates |
phosphorylation
dephosphorylation |
| gptkbp:structure |
multienzyme complex
|
| gptkbp:substrate |
gptkb:pyruvate
|
| gptkbp:subunit |
E1
|
| gptkbp:bfsParent |
gptkb:Vitamin_B1
|
| gptkbp:bfsLayer |
5
|