pyruvate decarboxylase

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:catalyzes decarboxylation of pyruvate to acetaldehyde and CO2
gptkbp:cofactor magnesium ion
thiamine pyrophosphate
gptkbp:compatibleWith animals
gptkbp:discoveredBy gptkb:Arthur_Harden
gptkbp:discoveredIn 1905
gptkbp:EC_number 4.1.1.1
gptkbp:foundIn gptkb:yeast
plants
gptkbp:gene gptkb:PDC1_(in_Saccharomyces_cerevisiae)
https://www.w3.org/2000/01/rdf-schema#label pyruvate decarboxylase
gptkbp:inhibitedBy high ethanol concentrations
gptkbp:involves alcoholic fermentation
gptkbp:molecularWeight ~60 kDa per subunit
gptkbp:optimum_pH 6.0-7.0
30-40°C
gptkbp:product carbon dioxide
acetaldehyde
gptkbp:structure tetramer
gptkbp:substrate gptkb:pyruvate
gptkbp:bfsParent gptkb:pyruvate
gptkbp:bfsLayer 6