Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:histidine_kinase
sensor kinase |
| gptkbp:compatibleWith |
animals
fungi |
| gptkbp:discoveredBy |
J. Adler
|
| gptkbp:discoveredIn |
1967
|
| gptkbp:EC_number |
2.7.13.3
|
| gptkbp:foundIn |
gptkb:Bacteria
plants archaea |
| gptkbp:function |
catalyzes the transfer of a phosphate group to a histidine residue
|
| gptkbp:GO_term |
GO:0000155
|
| https://www.w3.org/2000/01/rdf-schema#label |
protein histidine kinase
|
| gptkbp:involves |
two-component signal transduction system
|
| gptkbp:mechanismOfAction |
autophosphorylation
|
| gptkbp:Pfam_family |
PF00512
PF02518 |
| gptkbp:product |
gptkb:ADP
protein N-phospho-L-histidine |
| gptkbp:regulates |
response regulator proteins
|
| gptkbp:requires |
osmoregulation
bacterial chemotaxis sporulation virulence regulation |
| gptkbp:structure |
contains a HATPase_c domain
contains a conserved HisKA domain |
| gptkbp:substrate |
gptkb:ATP
protein L-histidine |
| gptkbp:target |
antimicrobial drug development
|
| gptkbp:UniProtID |
KW-0372
|
| gptkbp:bfsParent |
gptkb:EC_2.7.11.24
|
| gptkbp:bfsLayer |
7
|