Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
sensor kinase
|
| gptkbp:catalyzes |
phosphorylation of histidine residues
|
| gptkbp:cofactor |
gptkb:ATP
|
| gptkbp:compatibleWith |
animals
fungi |
| gptkbp:discoveredBy |
J. Adler
|
| gptkbp:domain |
HATPase_c domain
HisKA domain |
| gptkbp:EC_number |
2.7.13.3
|
| gptkbp:firstDescribed |
1970s
|
| gptkbp:foundIn |
gptkb:Bacteria
plants archaea |
| gptkbp:GO_term |
GO:0000155
|
| https://www.w3.org/2000/01/rdf-schema#label |
histidine kinase
|
| gptkbp:involvedIn |
two-component signal transduction system
|
| gptkbp:mechanismOfAction |
autophosphorylation
phosphotransfer to response regulator |
| gptkbp:presentIn |
prokaryotes
some eukaryotes |
| gptkbp:regulates |
cellular response to environmental stimuli
|
| gptkbp:role |
antibiotic resistance
biofilm formation osmoregulation bacterial chemotaxis sporulation virulence regulation |
| gptkbp:structure |
homodimer
|
| gptkbp:target |
antimicrobial drug development
|
| gptkbp:UniProtKeyword |
gptkb:Histidine_kinase
|
| gptkbp:bfsParent |
gptkb:EC_2.7.11.24
|
| gptkbp:bfsLayer |
7
|