Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:abbreviation |
gptkb:PDE1
|
| gptkbp:cofactor |
gptkb:calmodulin
calcium |
| gptkbp:EC_number |
3.1.4.17
|
| gptkbp:foundIn |
brain
heart vascular smooth muscle |
| gptkbp:function |
hydrolyzes cyclic nucleotides
|
| https://www.w3.org/2000/01/rdf-schema#label |
phosphodiesterase type 1
|
| gptkbp:inhibitedBy |
nimodipine
vinpocetine |
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:proteinFamily |
PDE1A
PDE1B PDE1C |
| gptkbp:regulates |
activated by Ca2+/calmodulin
|
| gptkbp:role |
signal transduction
regulation of intracellular cyclic nucleotide levels |
| gptkbp:substrate |
gptkb:cAMP
gptkb:cGMP |
| gptkbp:bfsParent |
gptkb:PDE1
gptkb:Phosphodiesterase |
| gptkbp:bfsLayer |
7
|