Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
small molecule |
| gptkbp:approvalYear |
2019
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
L01EX14
|
| gptkbp:brand |
gptkb:Turalio
|
| gptkbp:CASNumber |
1029044-16-3
|
| gptkbp:developer |
gptkb:Daiichi_Sankyo
|
| gptkbp:hasMolecularFormula |
C18H15F2N3O2S
|
| https://www.w3.org/2000/01/rdf-schema#label |
pexidartinib
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
CSF1R inhibitor
|
| gptkbp:pregnancyCategory |
not recommended
|
| gptkbp:PubChem_CID |
25154816
CHEMBL2036765 DB15086 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
nausea
vomiting fatigue hepatotoxicity dysgeusia hair color changes increased ALT increased AST |
| gptkbp:target |
gptkb:KIT
gptkb:FLT3 gptkb:CSF1R |
| gptkbp:UNII |
6Z5B6HVF6O
|
| gptkbp:usedFor |
tenosynovial giant cell tumor
|
| gptkbp:bfsParent |
gptkb:Plexxikon
|
| gptkbp:bfsLayer |
7
|