Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
|
gptkbp:approvalYear |
2019-08-02
|
gptkbp:ATCCode |
L01EX14
|
gptkbp:CASNumber |
1029044-16-3
|
gptkbp:chemicalFormula |
C22H15F2N5O2
|
gptkbp:contraindication |
pregnancy
severe hepatic impairment |
gptkbp:drugClass |
gptkb:receptor_tyrosine_kinase
|
gptkbp:genericName |
gptkb:pexidartinib
|
gptkbp:hasBoxedWarning |
hepatotoxicity
|
https://www.w3.org/2000/01/rdf-schema#label |
Turalio
|
gptkbp:indication |
tenosynovial giant cell tumor
|
gptkbp:legalStatus |
Rx-only
|
gptkbp:manufacturer |
gptkb:Daiichi_Sankyo
|
gptkbp:mechanismOfAction |
CSF1R inhibitor
|
gptkbp:pregnancyCategory |
D
|
gptkbp:prescriptionRequired |
https://www.turalio.com/
|
gptkbp:prescriptionStatus |
prescription only
|
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
nausea
vomiting diarrhea fatigue liver toxicity swelling dysgeusia hair color changes increased ALT increased AST |
gptkbp:bfsParent |
gptkb:Servier_Pharmaceuticals
|
gptkbp:bfsLayer |
7
|