|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:bfsLayer
|
5
|
|
gptkbp:bfsParent
|
gptkb:penicillin
|
|
gptkbp:activities
|
narrow spectrum
|
|
gptkbp:appointed_by
|
oral tablet
|
|
gptkbp:approves
|
1950s
|
|
gptkbp:availability
|
prescription only
|
|
gptkbp:brand
|
Pen VK
|
|
gptkbp:class
|
beta-lactam antibiotics
beta-lactam
thiazolidine
|
|
gptkbp:composed_of
|
semi-synthetic
|
|
gptkbp:contraindication
|
penicillin allergy
|
|
gptkbp:developed_by
|
gptkb:penicillin
|
|
gptkbp:discovered_by
|
gptkb:Alexander_Fleming
|
|
gptkbp:dosage_form
|
gptkb:tablet
suspension
250 mg to 500 mg
every 6 to 8 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:formulation
|
suspension
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
penicillin V
|
|
gptkbp:indication
|
gptkb:healthcare_organization
skin infections
otitis media
tonsillitis
pharyngitis
|
|
gptkbp:ingredients
|
C16 H17 N2 O5 S
|
|
gptkbp:interacts_with
|
gptkb:methotrexate
oral contraceptives
probenecid
|
|
gptkbp:invention
|
patent expired
|
|
gptkbp:is_used_for
|
bacterial infections
|
|
gptkbp:manager
|
oral
|
|
gptkbp:marketed_as
|
various pharmaceutical companies
|
|
gptkbp:metabolism
|
minimal hepatic metabolism
|
|
gptkbp:related_to
|
gptkb:penicillin_G
|
|
gptkbp:research_areas
|
pharmacokinetics
antibiotic resistance
dosage optimization
drug interactions
clinical efficacy
|
|
gptkbp:shelf_life
|
2 to 3 years
|
|
gptkbp:side_effect
|
nausea
allergic reactions
fever
seizures
diarrhea
rash
superinfection
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:targets
|
gptkb:Bacillus_anthracis
gptkb:Streptococcus_pyogenes
gptkb:Streptococcus_pneumoniae
Neisseria meningitidis
|