Statements (128)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:drug
|
gptkbp:bfsLayer |
4
|
gptkbp:bfsParent |
gptkb:cutaneous_anthrax
gptkb:inhalation_anthrax gptkb:injection_anthrax gptkb:Tuskegee_Syphilis_Study gptkb:Leptospirosis gptkb:Alexander_Fleming |
gptkbp:affects |
cell wall synthesis
|
gptkbp:appointed_by |
gptkb:Person
gptkb:mythological_figure injection oral route |
gptkbp:awards |
1945
|
gptkbp:contraindication |
severe renal impairment
penicillin allergy |
gptkbp:developed_by |
gptkb:amoxicillin
gptkb:Penicillium_chrysogenum gptkb:ampicillin beta-lactam antibiotics |
gptkbp:discovered_by |
gptkb:Alexander_Fleming
|
gptkbp:first_introduced |
gptkb:World_War_II
1940s |
gptkbp:form |
gptkb:penicillin_G
gptkb:penicillin_V |
gptkbp:has_impact_on |
modern medicine
Gram-positive bacteria |
https://www.w3.org/2000/01/rdf-schema#label |
penicillin
|
gptkbp:influenced_by |
gptkb:Ernst_Boris_Chain
gptkb:Howard_Florey |
gptkbp:interacts_with |
gptkb:methotrexate
probenecid |
gptkbp:invention |
gptkb:Ernst_Boris_Chain
gptkb:Howard_Florey |
gptkbp:is_a_source_of |
gptkb:Penicillium_notatum
gptkb:Penicillium_chrysogenum |
gptkbp:is_associated_with |
Fleming's discovery
|
gptkbp:is_available_on |
gptkb:product
gptkb:tablet intramuscular injection oral tablet intravenous injection injection solution |
gptkbp:is_considered |
first true antibiotic
life-saving drug |
gptkbp:is_considered_as |
breakthrough in medicine
|
gptkbp:is_effective_against |
gptkb:healthcare_organization
fungal infections viral infections strep throat |
gptkbp:is_part_of |
gptkb:WHO_essential_medicines_list
combination therapy antibiotic therapy antimicrobial stewardship |
gptkbp:is_protected_by |
gptkb:rheumatic_fever
|
gptkbp:is_recognized_by |
medical community
|
gptkbp:is_studied_in |
clinical trials
|
gptkbp:is_subject_to |
resistance
|
gptkbp:is_used_for |
gptkb:gonorrhea
gptkb:healthcare_organization gptkb:physicist gptkb:mythological_figure meningitis treating infections sepsis respiratory infections bacterial infections tetanus skin infections strep throat chlamydia preventing infections urinary tract infections endocarditis bacterial endocarditis bacterial vaginosis bacterial meningitis chancroid lymphogranuloma venereum |
gptkbp:is_used_in |
gptkb:hospital
hospital settings pediatrics emergency medicine outpatient care dentistry infectious disease treatment gynecology |
gptkbp:marketed_as |
gptkb:Penicillin_G_potassium
gptkb:Penicillin_V_potassium |
gptkbp:mass |
1940s
|
gptkbp:produced_by |
gptkb:Penicillium_mold
1943 fermentation fermentation process |
gptkbp:side_effect |
allergic reactions
|
gptkbp:storage |
refrigeration
|
gptkbp:type |
beta-lactam antibiotic
|
gptkbp:used_in |
gptkb:hospital
pediatrics dentistry infectious disease treatment treatment of tetanus treatment of diphtheria treatment of cholera treatment of gonorrhea treatment of meningitis treatment of plague treatment of typhoid fever treatment of respiratory infections treatment of skin infections treatment of urinary tract infections treatment of Q fever treatment of actinomycosis treatment of anthrax treatment of botulism treatment of brucellosis treatment of clostridial infections treatment of endocarditis treatment of leptospirosis treatment of listeriosis treatment of rheumatic fever treatment of salmonellosis treatment of shigellosis treatment of tularemia treatment of vibrio infections treatment of yersiniosis |
gptkbp:water_resistance |
bacterial resistance
|
gptkbp:year_created |
1928
|