Statements (125)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:pharmaceuticals
|
| gptkbp:administered_by |
gptkb:animals
gptkb:humans injection oral route |
| gptkbp:affects |
cell wall synthesis
|
| gptkbp:available_on |
gptkb:tablet
gptkb:Sugar intramuscular injection oral tablet intravenous injection injection solution |
| gptkbp:contraindication |
severe renal impairment
penicillin allergy |
| gptkbp:developed_by |
gptkb:amoxicillin
gptkb:Penicillium_chrysogenum gptkb:ampicillin |
| gptkbp:discovered_by |
gptkb:Alexander_Fleming
|
| gptkbp:discovery_year |
1928
|
| gptkbp:first_introduced |
gptkb:World_War_II
1940s |
| gptkbp:first_mass_produced |
1940s
|
| gptkbp:form |
gptkb:penicillin_G
gptkb:penicillin_V |
| gptkbp:has_impact_on |
modern medicine
Gram-positive bacteria |
| https://www.w3.org/2000/01/rdf-schema#label |
penicillin
|
| gptkbp:influenced_by |
gptkb:Ernst_Boris_Chain
gptkb:Howard_Florey |
| gptkbp:interacts_with |
gptkb:methotrexate
probenecid |
| gptkbp:invention |
gptkb:Ernst_Boris_Chain
gptkb:Howard_Florey |
| gptkbp:is_a_source_of |
gptkb:Penicillium_notatum
gptkb:Penicillium_chrysogenum |
| gptkbp:is_associated_with |
Fleming's discovery
|
| gptkbp:is_considered |
first true antibiotic
life-saving drug |
| gptkbp:is_effective_against |
gptkb:disease
gptkb:pneumonia fungal infections viral infections strep throat |
| gptkbp:is_part_of |
gptkb:WHO_essential_medicines_list
combination therapy antibiotic therapy antimicrobial stewardship |
| gptkbp:is_protected_by |
gptkb:rheumatic_fever
|
| gptkbp:is_recognized_by |
medical community
|
| gptkbp:is_regarded_as |
breakthrough in medicine
|
| gptkbp:is_studied_in |
clinical trials
|
| gptkbp:is_subject_to |
resistance
|
| gptkbp:is_used_for |
gptkb:gonorrhea
gptkb:disease gptkb:botulism meningitis treating infections sepsis respiratory infections bacterial infections tetanus skin infections chlamydia preventing infections urinary tract infections endocarditis bacterial endocarditis bacterial vaginosis bacterial meningitis chancroid lymphogranuloma venereum |
| gptkbp:is_used_in |
gptkb:surgery
hospital settings pediatrics emergency medicine outpatient care dentistry infectious disease treatment gynecology |
| gptkbp:led_to_development_of |
beta-lactam antibiotics
|
| gptkbp:marketed_as |
gptkb:Penicillin_G_potassium
gptkb:Penicillin_V_potassium |
| gptkbp:produced_by |
gptkb:Penicillium_mold
fermentation fermentation process |
| gptkbp:side_effect |
allergic reactions
|
| gptkbp:storage |
refrigeration
|
| gptkbp:type |
beta-lactam antibiotic
|
| gptkbp:used_for |
gptkb:disease
gptkb:pneumonia strep throat |
| gptkbp:used_in |
gptkb:surgery
pediatrics dentistry infectious disease treatment treatment of tetanus treatment of diphtheria treatment of cholera treatment of gonorrhea treatment of meningitis treatment of plague treatment of typhoid fever treatment of respiratory infections treatment of skin infections treatment of urinary tract infections treatment of Q fever treatment of actinomycosis treatment of anthrax treatment of botulism treatment of brucellosis treatment of clostridial infections treatment of endocarditis treatment of leptospirosis treatment of listeriosis treatment of rheumatic fever treatment of salmonellosis treatment of shigellosis treatment of tularemia treatment of vibrio infections treatment of yersiniosis |
| gptkbp:was_mass_produced_in |
1943
|
| gptkbp:water_resistance |
bacterial resistance
|
| gptkbp:won_nobel_prize_in |
1945
|
| gptkbp:bfsParent |
gptkb:Tuskegee_Syphilis_Study
|
| gptkbp:bfsLayer |
4
|