Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
pVHL19
pVHL30 |
| gptkbp:binds |
gptkb:hypoxia-inducible_factor_(HIF)
|
| gptkbp:encodedBy |
gptkb:VHL_gene
|
| gptkbp:formsComplexWith |
gptkb:cullin_2
elongin B elongin C Rbx1 |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
tumor suppressor
|
| https://www.w3.org/2000/01/rdf-schema#label |
pVHL protein
|
| gptkbp:involvedIn |
ubiquitin-mediated proteolysis
|
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:locatedOnChromosome |
3p25-26
|
| gptkbp:molecularWeight |
24 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:von_Hippel-Lindau_disease
clear cell renal cell carcinoma |
| gptkbp:PDB |
gptkb:1LM8
|
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination |
| gptkbp:regulates |
cellular response to oxygen levels
|
| gptkbp:UniProtID |
P40337
|
| gptkbp:bfsParent |
gptkb:VHL
|
| gptkbp:bfsLayer |
6
|