p38 MAPK family

GPTKB entity

Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy environmental stress
pro-inflammatory cytokines
gptkbp:affiliatedWith gptkb:MAP_kinase_family
gptkbp:alsoKnownAs MAPK14 family
gptkbp:discoveredIn 1994
gptkbp:EC_number 2.7.11.24
gptkbp:expressedIn mammals
gptkbp:function signal transduction
apoptosis regulation
inflammatory response
cellular response to stress
https://www.w3.org/2000/01/rdf-schema#label p38 MAPK family
gptkbp:inhibitedBy gptkb:SB203580
gptkb:BIRB_796
gptkbp:involvedIn cell differentiation
cell cycle regulation
neurodegenerative diseases
cancer progression
inflammatory diseases
immune response
gptkbp:locatedOnChromosome chromosome 22 (MAPK11)
chromosome 22 (MAPK12)
chromosome 6 (MAPK13)
chromosome 6 (MAPK14)
gptkbp:member gptkb:MAPK11
gptkb:MAPK12
gptkb:MAPK13
gptkb:MAPK14
gptkbp:phosphorylates transcription factors
cytoskeletal proteins
protein kinases
gptkbp:relatedTo JNK family
ERK family
gptkbp:bfsParent gptkb:p38_alpha
gptkbp:bfsLayer 7