orotidine-5'-phosphate decarboxylase
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
ODCase
OMP decarboxylase OMPdecase |
| gptkbp:CASNumber |
9024-62-4
|
| gptkbp:catalyzes |
decarboxylation of orotidine 5'-monophosphate to uridine 5'-monophosphate
|
| gptkbp:cofactor |
none
|
| gptkbp:EC_number |
4.1.1.23
|
| gptkbp:foundIn |
all domains of life
|
| gptkbp:gene |
UMPS
|
| gptkbp:gene_symbol_(yeast) |
gptkb:URA3
|
| https://www.w3.org/2000/01/rdf-schema#label |
orotidine-5'-phosphate decarboxylase
|
| gptkbp:involves |
pyrimidine biosynthesis
|
| gptkbp:organism_example |
gptkb:Saccharomyces_cerevisiae
gptkb:Homo_sapiens gptkb:Bacteria |
| gptkbp:pathway |
de novo pyrimidine biosynthesis
|
| gptkbp:PDB |
1DQX
|
| gptkbp:product |
uridine 5'-monophosphate
|
| gptkbp:remarkable_for |
one of the highest rate enhancements of any known enzyme
|
| gptkbp:requires |
de novo synthesis of pyrimidine nucleotides
|
| gptkbp:structure |
homodimer in many species
|
| gptkbp:substrate |
orotidine 5'-monophosphate
|
| gptkbp:systematicName |
orotidine-5'-phosphate carboxy-lyase
|
| gptkbp:type |
orotidine 5'-phosphate → uridine 5'-phosphate + CO2
|
| gptkbp:UniProtID |
P11172
|
| gptkbp:bfsParent |
gptkb:URA3
gptkb:URA_gene |
| gptkbp:bfsLayer |
7
|