Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:discoveredIn |
1986
|
| gptkbp:encodes |
gptkb:Nef_protein
|
| gptkbp:foundIn |
gptkb:HIV-1
gptkb:HIV-2 |
| gptkbp:function |
downregulation of CD4
downregulation of MHC I enhancement of viral infectivity modulation of T cell activation |
| https://www.w3.org/2000/01/rdf-schema#label |
nef gene
|
| gptkbp:interactsWith |
host cell proteins
|
| gptkbp:involvedIn |
immune evasion
|
| gptkbp:length |
approximately 600 nucleotides
|
| gptkbp:location |
gptkb:HIV_genome
|
| gptkbp:mutationAssociatedWith |
attenuated HIV pathogenicity
|
| gptkbp:nameMeaning |
Negative factor
|
| gptkbp:regulates |
cell surface receptors
|
| gptkbp:requires |
optimal viral replication
|
| gptkbp:target |
HIV research
|
| gptkbp:bfsParent |
gptkb:Nef_(protein)
|
| gptkbp:bfsLayer |
7
|