myosin light-chain kinase

URI: https://gptkb.org/entity/myosin_light-chain_kinase
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:activatedBy calcium ions
gptkbp:alternativeName gptkb:MLCK
gptkb:myosin_light_chain_kinase
gptkbp:associatedWith asthma
inflammatory bowel disease
gptkbp:biologicalProcess cytoskeleton organization
muscle contraction
cell motility
protein serine/threonine kinase activity
gptkbp:catalyzes phosphorylation of myosin light chains
gptkbp:cofactor gptkb:calmodulin
gptkbp:EC_number 2.7.11.18
gptkbp:foundIn gptkb:skeletal_muscle
cardiac muscle
smooth muscle
gptkbp:function regulates muscle contraction
gptkbp:gene gptkb:MYLK
gptkbp:gene_symbol_(rat) gptkb:Mylk
https://www.w3.org/2000/01/rdf-schema#label myosin light-chain kinase
gptkbp:inhibitedBy gptkb:ML-7
gptkb:ML-9
gptkbp:OMIM 600922
gptkbp:phosphorylates serine residue
threonine residue
gptkbp:structure contains kinase domain
contains calmodulin-binding domain
gptkbp:substrate myosin regulatory light chain
gptkbp:UniProtID gptkb:Q15746
gptkbp:bfsParent gptkb:wortmannin
gptkbp:bfsLayer 5