muscarinic acetylcholine receptor M1
GPTKB entity
Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:alternativeName |
gptkb:CHRM1
M1 receptor muscarinic receptor M1 |
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
schizophrenia cognitive disorders |
| gptkbp:binds |
gptkb:muscarine
gptkb:acetylcholine |
| gptkbp:encodedBy |
CHRM1 gene
|
| gptkbp:enemyOf |
gptkb:pilocarpine
atropine oxotremorine pirenzepine |
| gptkbp:Entrez_Gene_ID |
1128
|
| gptkbp:foundIn |
gptkb:human
mammals |
| gptkbp:function |
regulation of memory
regulation of learning modulation of cognitive function |
| https://www.w3.org/2000/01/rdf-schema#label |
muscarinic acetylcholine receptor M1
|
| gptkbp:improves |
phospholipase C activity
intracellular calcium inositol trisphosphate production |
| gptkbp:locatedIn |
gptkb:cerebral_cortex
central nervous system hippocampus exocrine glands |
| gptkbp:locatedOnChromosome |
gptkb:11q13
|
| gptkbp:type |
Gq/11 protein pathway
|
| gptkbp:UniProtID |
P11229
|
| gptkbp:bfsParent |
gptkb:xanomeline
gptkb:CHRM1 |
| gptkbp:bfsLayer |
7
|