|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
Cornelia de Lange syndrome (in human ortholog)
|
|
gptkbp:biologicalProcess
|
chromatin modification
transcriptional repression
NAD-independent histone deacetylase activity
|
|
gptkbp:Entrez_Gene_ID
|
233071
|
|
gptkbp:enzymeCommissionNumber
|
gptkb:EC_3.5.1.98
|
|
gptkbp:expressedIn
|
gptkb:kidney
gptkb:testis
brain
heart
liver
|
|
gptkbp:family
|
histone deacetylase family
|
|
gptkbp:fullName
|
gptkb:Histone_deacetylase_8
|
|
gptkbp:function
|
regulation of gene expression
histone deacetylation
|
|
gptkbp:gene
|
Hdac8
|
|
gptkbp:hasIsoform
|
Hdac8-201
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
mouse Hdac8
|
|
gptkbp:inhibitedBy
|
Suberoylanilide hydroxamic acid (SAHA)
Trichostatin A
|
|
gptkbp:length
|
377 amino acids
|
|
gptkbp:locatedOnChromosome
|
X
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:molecularWeight
|
42 kDa
|
|
gptkbp:organism
|
gptkb:Mus_musculus
|
|
gptkbp:orthologIn
|
human HDAC8
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:structure
|
contains HDAC domain
|
|
gptkbp:UniProtID
|
Q9JHD2
|
|
gptkbp:bfsParent
|
gptkb:HDAC8
|
|
gptkbp:bfsLayer
|
8
|