Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:HDAC8
histone deacetylase 8, isoform 1 |
| gptkbp:associatedWith |
gptkb:Cornelia_de_Lange_syndrome
|
| gptkbp:EC_number |
3.5.1.98
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
regulates gene expression
regulates chromatin structure removes acetyl groups from histones |
| https://www.w3.org/2000/01/rdf-schema#label |
Histone deacetylase 8
|
| gptkbp:inhibitedBy |
gptkb:PCI-34051
Trichostatin A |
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
Xq13.1
|
| gptkbp:member |
histone deacetylase family
|
| gptkbp:molecularWeight |
~42 kDa
|
| gptkbp:PDB |
gptkb:1T64
|
| gptkbp:product |
gptkb:HDAC8_gene
|
| gptkbp:structure |
contains deacetylase domain
|
| gptkbp:UniProtID |
gptkb:Q9BY41
|
| gptkbp:bfsParent |
gptkb:HDAC8
|
| gptkbp:bfsLayer |
8
|