Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
gptkb:ATP-binding_cassette_sub-family_A_member_1
CERP (cholesterol efflux regulatory protein) |
| gptkbp:associatedWith |
Tangier disease (in humans)
|
| gptkbp:encodes |
ATP-binding cassette transporter A1
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSMUSG00000022868
11303 |
| gptkbp:expressedIn |
liver
adipose tissue macrophages intestine |
| gptkbp:function |
cholesterol efflux
phospholipid efflux |
| gptkbp:gene |
Abca1
|
| gptkbp:GO_term |
GO:0005319 (lipid transporter activity)
GO:0033344 (cholesterol efflux) |
| https://www.w3.org/2000/01/rdf-schema#label |
mouse Abca1
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_4
|
| gptkbp:mutationAssociatedWith |
impaired cholesterol efflux
reduced plasma HDL cholesterol |
| gptkbp:organism |
gptkb:Mus_musculus
|
| gptkbp:orthologIn |
human ABCA1
|
| gptkbp:proteinFamily |
gptkb:ABC_transporter_family
|
| gptkbp:regulates |
HDL formation
|
| gptkbp:UniProtID |
O55144
|
| gptkbp:bfsParent |
gptkb:ABCA1
|
| gptkbp:bfsLayer |
7
|