Statements (38)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
medical condition
|
| gptkbp:affects |
tissues
organs |
| gptkbp:alsoKnownAs |
I/R injury
|
| gptkbp:cause |
apoptosis
inflammation oxidative stress cell death necrosis |
| gptkbp:commonIn |
gptkb:trauma
myocardial infarction stroke organ transplantation |
| gptkbp:firstDescribed |
20th century
|
| https://www.w3.org/2000/01/rdf-schema#label |
ischemia-reperfusion injury
|
| gptkbp:mechanismOfAction |
inflammatory response
calcium overload endothelial dysfunction generation of reactive oxygen species restoration of blood flow after ischemia |
| gptkbp:relatedTo |
inflammation
oxidative stress reperfusion therapy |
| gptkbp:riskFactor |
advanced age
comorbidities prolonged ischemia |
| gptkbp:studiedIn |
cardiology
neurology nephrology transplant medicine |
| gptkbp:treatment |
antioxidants
calcium channel blockers anti-inflammatory drugs therapeutic hypothermia ischemic preconditioning |
| gptkbp:bfsParent |
gptkb:KIM-1
gptkb:superoxide_dismutase |
| gptkbp:bfsLayer |
7
|