|
gptkbp:instanceOf
|
antifungal medication
imidazole derivative
|
|
gptkbp:ATCCode
|
D01AC02
|
|
gptkbp:brand
|
gptkb:Monistat
gptkb:Daktarin
Micatin
|
|
gptkbp:CASNumber
|
22916-47-8
|
|
gptkbp:contraindication
|
hypersensitivity to imidazoles
|
|
gptkbp:discoveredBy
|
gptkb:Janssen_Pharmaceutica
|
|
gptkbp:discoveredIn
|
1969
|
|
gptkbp:drugInteraction
|
gptkb:phenytoin
gptkb:warfarin
oral hypoglycemics
|
|
gptkbp:eliminationHalfLife
|
24 hours
|
|
gptkbp:excretion
|
urine
bile
|
|
gptkbp:hasMolecularFormula
|
C18H14Cl4N2O
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
miconazole
|
|
gptkbp:KEGGID
|
D00418
|
|
gptkbp:legalStatus
|
OTC (over-the-counter)
|
|
gptkbp:mechanismOfAction
|
inhibits ergosterol synthesis
|
|
gptkbp:meltingPoint
|
178–180 °C
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL137
4189
4044
DB01110
|
|
gptkbp:routeOfAdministration
|
topical
vaginal
oral gel
|
|
gptkbp:sideEffect
|
skin irritation
burning sensation
redness
|
|
gptkbp:solubility
|
practically insoluble in water
|
|
gptkbp:UNII
|
VW4H1CYW1K
|
|
gptkbp:usedFor
|
treatment of fungal infections
treatment of athlete's foot
treatment of jock itch
treatment of ringworm
treatment of vaginal yeast infections
|
|
gptkbp:bfsParent
|
gptkb:CYP3A5
gptkb:vulvovaginal_candidiasis
|
|
gptkbp:bfsLayer
|
6
|