|
gptkbp:instanceOf
|
gptkb:antibiotic
antiprotozoal drug
|
|
gptkbp:ATCCode
|
J01XD01
|
|
gptkbp:brand
|
Flagyl
Metrogel
Noritate
Rozex
|
|
gptkbp:CASNumber
|
443-48-1
|
|
gptkbp:chemicalFormula
|
C6H9N3O3
|
|
gptkbp:contraindication
|
alcohol consumption
first trimester of pregnancy
|
|
gptkbp:discoveredBy
|
1960
J. T. Dickison
|
|
gptkbp:drugbank_ID
|
DB00916
|
|
gptkbp:eliminationHalfLife
|
8 hours
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:first_approved_by_FDA
|
1963
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
metronidazole
|
|
gptkbp:KEGGID
|
D00428
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits nucleic acid synthesis
|
|
gptkbp:meltingPoint
|
159 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
171.16 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:PubChem_CID
|
4173
CHEBI:6909
|
|
gptkbp:riskFactor
|
disulfiram-like reaction with alcohol
|
|
gptkbp:routeOfAdministration
|
oral
topical
vaginal
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
dizziness
headache
rash
metallic taste
|
|
gptkbp:solubility
|
slightly soluble
|
|
gptkbp:UNII
|
140QMO216E
|
|
gptkbp:used_in_veterinary_medicine
|
yes
|
|
gptkbp:usedFor
|
gptkb:Clostridioides_difficile_infection
amebiasis
giardiasis
pelvic inflammatory disease
trichomoniasis
rosacea
dental infections
bacterial vaginosis
anaerobic bacterial infections
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Giardiasis
gptkb:Clostridioides_difficile_infection
|
|
gptkbp:bfsLayer
|
5
|