melanocortin 4 receptor

GPTKB entity

Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:G_protein-coupled_receptor
gptkbp:alternativeName gptkb:MC4R
MC4 receptor
gptkbp:associatedWith obesity
gptkbp:biologicalProcess G protein-coupled receptor activity
neuropeptide receptor activity
gptkbp:enemyOf gptkb:alpha-melanocyte-stimulating_hormone
agouti-related peptide
gptkbp:Entrez_Gene_ID 4160
gptkbp:expressedIn brain
hypothalamus
gptkbp:foundIn gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:function regulation of appetite
regulation of body weight
regulation of energy homeostasis
gptkbp:gene gptkb:MC4R
https://www.w3.org/2000/01/rdf-schema#label melanocortin 4 receptor
gptkbp:length 332
gptkbp:ligand gptkb:alpha-melanocyte-stimulating_hormone
agouti-related peptide
gptkbp:locatedOnChromosome 18q21.32
gptkbp:mutationAssociatedWith monogenic obesity
gptkbp:OMIM 155541
gptkbp:pathway melanocortin signaling pathway
gptkbp:PDB 6W25
gptkbp:relatedTo energy expenditure
feeding behavior
gptkbp:UniProtID P32245
gptkbp:bfsParent gptkb:alpha-MSH
gptkb:alpha-melanocyte-stimulating_hormone
gptkb:MC4R
gptkbp:bfsLayer 7