mechlorethamine

GPTKB entity

Statements (42)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
antineoplastic agent
nitrogen mustard
gptkbp:ATCCode L01AA05
gptkbp:brand Mustargen
Valchlor
gptkbp:CASNumber 51-75-2
gptkbp:category World Health Organization essential medicine
gptkbp:chemicalFormula C5H11Cl2N
gptkbp:discoveredBy gptkb:Alfred_Gilman
Louis Goodman
gptkbp:discoveredIn 1942
gptkbp:eliminationHalfLife <1 minute (plasma)
gptkbp:excretion renal
https://www.w3.org/2000/01/rdf-schema#label mechlorethamine
gptkbp:IUPACName 2-chloro-N-(2-chloroethyl)-N-methylethan-1-amine
gptkbp:KEGGID D00480
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction antineoplastic agent
gptkbp:meltingPoint 70 °C
gptkbp:metabolism hepatic
gptkbp:molecularWeight 156.06 g/mol
gptkbp:pregnancyCategory D (US)
gptkbp:PubChem_CID gptkb:CHEMBL608
4033
DB00888
gptkbp:routeOfAdministration topical
intravenous
gptkbp:sideEffect nausea
vomiting
hair loss
infertility
secondary malignancy
bone marrow suppression
gptkbp:solubility soluble in water
gptkbp:toxicity highly toxic
gptkbp:UNII 50D430A51U
gptkbp:usedFor gptkb:cancer
leukemia
Hodgkin lymphoma
gptkbp:bfsParent gptkb:nitrogen_mustard
gptkbp:bfsLayer 7