gptkbp:instanceOf
|
gptkb:chemical_compound
antineoplastic agent
nitrogen mustard
|
gptkbp:ATCCode
|
L01AA05
|
gptkbp:brand
|
Mustargen
Valchlor
|
gptkbp:CASNumber
|
51-75-2
|
gptkbp:category
|
World Health Organization essential medicine
|
gptkbp:chemicalFormula
|
C5H11Cl2N
|
gptkbp:discoveredBy
|
gptkb:Alfred_Gilman
Louis Goodman
|
gptkbp:discoveredIn
|
1942
|
gptkbp:eliminationHalfLife
|
<1 minute (plasma)
|
gptkbp:excretion
|
renal
|
https://www.w3.org/2000/01/rdf-schema#label
|
mechlorethamine
|
gptkbp:IUPACName
|
2-chloro-N-(2-chloroethyl)-N-methylethan-1-amine
|
gptkbp:KEGGID
|
D00480
|
gptkbp:legalStatus
|
prescription only
|
gptkbp:mechanismOfAction
|
antineoplastic agent
|
gptkbp:meltingPoint
|
70 °C
|
gptkbp:metabolism
|
hepatic
|
gptkbp:molecularWeight
|
156.06 g/mol
|
gptkbp:pregnancyCategory
|
D (US)
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL608
4033
DB00888
|
gptkbp:routeOfAdministration
|
topical
intravenous
|
gptkbp:sideEffect
|
nausea
vomiting
hair loss
infertility
secondary malignancy
bone marrow suppression
|
gptkbp:solubility
|
soluble in water
|
gptkbp:toxicity
|
highly toxic
|
gptkbp:UNII
|
50D430A51U
|
gptkbp:usedFor
|
gptkb:cancer
leukemia
Hodgkin lymphoma
|
gptkbp:bfsParent
|
gptkb:nitrogen_mustard
|
gptkbp:bfsLayer
|
7
|