Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
leukemia |
| gptkbp:affects |
gptkb:mast_cells
|
| gptkbp:cause |
hepatosplenomegaly
organ dysfunction skin lesions cytopenias |
| gptkbp:characterizedBy |
abnormal proliferation of mast cells
|
| gptkbp:diagnosedBy |
bone marrow biopsy
immunophenotyping peripheral blood smear |
| gptkbp:firstDescribed |
1950
|
| gptkbp:hasGeneticAlteration |
gptkb:KIT_D816V_mutation
|
| gptkbp:hasMedianSurvival |
less than 1 year
|
| gptkbp:hasType |
neoplastic mast cell
|
| https://www.w3.org/2000/01/rdf-schema#label |
mast cell leukemia
|
| gptkbp:ICD-10_code |
C96.2
|
| gptkbp:prevalence |
very rare
|
| gptkbp:prognosis |
poor
|
| gptkbp:subclassOf |
gptkb:systemic_mastocytosis
|
| gptkbp:symptom |
gptkb:anemia
fever diarrhea bleeding abdominal pain fatigue weight loss flushing |
| gptkbp:treatment |
chemotherapy
stem cell transplantation tyrosine kinase inhibitors |
| gptkbp:bfsParent |
gptkb:systemic_mastocytosis
|
| gptkbp:bfsLayer |
6
|