|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
muscular dystrophy
|
|
gptkbp:binds
|
gptkb:laminin
gptkb:agrin
perlecan
|
|
gptkbp:component
|
gptkb:dystrophin-glycoprotein_complex
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:encodedBy
|
gptkb:DAG1_gene
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
epithelial cells
|
|
gptkbp:foundIn
|
gptkb:cell_membrane
|
|
gptkbp:function
|
links extracellular matrix to cytoskeleton
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dystroglycan
|
|
gptkbp:interactsWith
|
gptkb:syntrophin
gptkb:utrophin
gptkb:dystrophin
gptkb:alpha-dystrobrevin
|
|
gptkbp:location
|
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
156 kDa (alpha), 43 kDa (beta)
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Walker-Warburg_syndrome
muscular dystrophy
muscle-eye-brain disease
|
|
gptkbp:OMIM
|
128239
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:C._elegans
gptkb:zebrafish
|
|
gptkbp:postTranslationalModification
|
glycosylation
|
|
gptkbp:role
|
signal transduction
cell adhesion
maintenance of muscle integrity
|
|
gptkbp:subunit
|
gptkb:beta-dystroglycan
gptkb:alpha-dystroglycan
|
|
gptkbp:UniProtID
|
Q14118
|
|
gptkbp:bfsParent
|
gptkb:dystrophin-glycoprotein_complex
gptkb:Laminin_alpha_chain
gptkb:laminin
|
|
gptkbp:bfsLayer
|
7
|