Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
natural product
protease inhibitor |
| gptkbp:application |
study of ubiquitin-proteasome pathway
|
| gptkbp:CASNumber |
133343-34-7
|
| gptkbp:chemicalFormula |
C15H24N2O6
|
| gptkbp:discoveredBy |
Omura Satoshi
|
| gptkbp:discoveredIn |
1991
|
| gptkbp:effect |
induces apoptosis in some cell types
|
| https://www.w3.org/2000/01/rdf-schema#label |
lactacystin
|
| gptkbp:IUPACName |
(2S,3R,4S)-4-[(1R)-1-hydroxy-2-oxo-2-[(2S)-2-oxopyrrolidin-1-yl]ethyl]-3-methyl-2-(prop-2-en-1-yl)oxetan-2-yl acetate
|
| gptkbp:mechanismOfAction |
irreversible proteasome inhibition
|
| gptkbp:molecularWeight |
328.36 g/mol
|
| gptkbp:producedBy |
Streptomyces lactacystinaeus
|
| gptkbp:PubChem_CID |
9831462
|
| gptkbp:relatedTo |
clasto-lactacystin β-lactone
|
| gptkbp:solubility |
soluble in DMSO
|
| gptkbp:synonym |
N-acetylcysteinyl-leucine-lactone
|
| gptkbp:usedIn |
biological research
|
| gptkbp:bfsParent |
gptkb:proteasome
|
| gptkbp:bfsLayer |
7
|