kynurenine monooxygenase (KMO)
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:kynurenine_3-monooxygenase
kynurenine 3-hydroxylase |
| gptkbp:associatedWith |
neurodegenerative diseases
|
| gptkbp:catalyzes |
hydroxylation of L-kynurenine to 3-hydroxykynurenine
|
| gptkbp:cofactor |
gptkb:FAD
NADPH |
| gptkbp:EC_number |
1.14.13.9
|
| gptkbp:gene |
gptkb:KMO
|
| https://www.w3.org/2000/01/rdf-schema#label |
kynurenine monooxygenase (KMO)
|
| gptkbp:inhibitedBy |
Ro 61-8048
|
| gptkbp:locatedIn |
mitochondrial outer membrane
|
| gptkbp:locatedOnChromosome |
1q42
|
| gptkbp:organism |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:pathway |
tryptophan catabolism
|
| gptkbp:PDB |
4J36
5NAK |
| gptkbp:product |
gptkb:3-hydroxykynurenine
|
| gptkbp:relatedTo |
gptkb:Alzheimer's_disease
gptkb:Huntington's_disease schizophrenia inflammation |
| gptkbp:substrate |
L-kynurenine
|
| gptkbp:UniProtID |
Q8NEG4 (human)
|
| gptkbp:bfsParent |
gptkb:Kynurenine_pathway
|
| gptkbp:bfsLayer |
8
|