|
gptkbp:instanceOf
|
nonsteroidal anti-inflammatory drug
|
|
gptkbp:approvedBy
|
1989
|
|
gptkbp:ATCCode
|
M01AB15
|
|
gptkbp:brand
|
gptkb:Acular
gptkb:Toradol
|
|
gptkbp:CASNumber
|
74103-06-3
|
|
gptkbp:chemicalFormula
|
C15H13NO3
|
|
gptkbp:contraindication
|
renal failure
peptic ulcer
hypersensitivity to NSAIDs
|
|
gptkbp:discoveredBy
|
gptkb:Syntex
|
|
gptkbp:drugClass
|
gptkb:NSAID
|
|
gptkbp:eliminationHalfLife
|
4-6 hours
|
|
gptkbp:excretion
|
urine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ketorolac
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:maximumDurationOfUse
|
5 days (systemic use)
|
|
gptkbp:mechanismOfAction
|
COX inhibitor
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:notRecommendedFor
|
children under 2 years
|
|
gptkbp:pregnancyCategory
|
C (first and second trimester)
D (third trimester)
|
|
gptkbp:riskFactor
|
cardiovascular events
increased bleeding
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
ophthalmic
|
|
gptkbp:sideEffect
|
headache
gastrointestinal bleeding
drowsiness
renal impairment
|
|
gptkbp:UNII
|
YQT2285Y6C
|
|
gptkbp:usedFor
|
pain management
|
|
gptkbp:bfsParent
|
gptkb:NSAIDs
|
|
gptkbp:bfsLayer
|
6
|