Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:KS
3-oxoacyl-ACP synthase |
| gptkbp:biologicalProcess |
transferase activity
fatty acid biosynthetic process |
| gptkbp:catalytic_mechanism |
gptkb:Claisen_condensation
|
| gptkbp:cofactor |
none (does not require cofactors)
|
| gptkbp:EC_number |
2.3.1.-
|
| gptkbp:foundIn |
gptkb:Bacteria
animals plants |
| gptkbp:function |
catalyzes condensation reactions in fatty acid synthesis
|
| gptkbp:gene |
fabB
fabF fabH |
| gptkbp:hasIsoform |
KAS I
KAS II KAS III |
| https://www.w3.org/2000/01/rdf-schema#label |
ketoacyl synthase
|
| gptkbp:inhibitedBy |
gptkb:cerulenin
thiolactomycin |
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:part_of |
gptkb:fatty_acid_synthase_complex
|
| gptkbp:PDB |
2VZ8
1FJ4 |
| gptkbp:product |
beta-ketoacyl-ACP
|
| gptkbp:structure |
homodimer or homotetramer
|
| gptkbp:substrate |
acyl carrier protein (ACP)
malonyl-ACP |
| gptkbp:bfsParent |
gptkb:fatty_acid_synthase_complex
|
| gptkbp:bfsLayer |
7
|