Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
ionotropic glutamate receptor
|
| gptkbp:associatedWith |
epilepsy
neurodegenerative diseases |
| gptkbp:category |
gptkb:cell_membrane
neurotransmitter receptor |
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:GRIK1
gptkb:GRIK2 gptkb:GRIK3 gptkb:GRIK4 gptkb:GRIK5 |
| gptkbp:enemyOf |
gptkb:CNQX
gptkb:NBQX gptkb:UBP302 |
| gptkbp:foundIn |
central nervous system
|
| gptkbp:function |
mediates excitatory neurotransmission
|
| https://www.w3.org/2000/01/rdf-schema#label |
kainate receptor
|
| gptkbp:ligand |
gptkb:kainic_acid
glutamate |
| gptkbp:location |
postsynaptic membrane
presynaptic membrane |
| gptkbp:modulatedBy |
gptkb:synaptic_plasticity
neurotransmitter release |
| gptkbp:permeableTo |
calcium ions
potassium ions sodium ions |
| gptkbp:relatedTo |
gptkb:AMPA_receptor
gptkb:NMDA_receptor |
| gptkbp:structure |
tetrameric protein complex
|
| gptkbp:subunit |
gptkb:GluK1
gptkb:GluK2 gptkb:GluK3 gptkb:GluK4 gptkb:GluK5 |
| gptkbp:bfsParent |
gptkb:AMBA_family
|
| gptkbp:bfsLayer |
6
|