Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:bfsLayer |
4
|
| gptkbp:bfsParent |
gptkb:Zantac
gptkb:Nexium |
| gptkbp:activities |
inhibits fungal sterol synthesis
|
| gptkbp:appointed_by |
oral capsule
oral solution intravenous injection |
| gptkbp:approves |
gptkb:1992
gptkb:FDA |
| gptkbp:brand |
gptkb:Sporanox
Onmel |
| gptkbp:caused_by |
hypertension
heart failure rash hypokalemia anaphylaxis hepatotoxicity peripheral edema |
| gptkbp:contraindication |
liver disease
pregnancy |
| gptkbp:developed_by |
gptkb:Janssen_Pharmaceuticals
|
| gptkbp:excretion |
urine
|
| https://www.w3.org/2000/01/rdf-schema#label |
itraconazole
|
| gptkbp:ingredients |
C35 H38 Cl2 N4 O4 S
|
| gptkbp:interacts_with |
gptkb:cyclosporine
gptkb:warfarin benzodiazepines statins |
| gptkbp:is_atype_of |
J02 A C02
|
| gptkbp:is_available_in |
oral and intravenous forms
|
| gptkbp:is_available_on |
generic drug
|
| gptkbp:is_monitored_by |
heart function
liver function |
| gptkbp:is_part_of |
azole class of antifungals
|
| gptkbp:is_used_for |
treating fungal infections
|
| gptkbp:lifespan |
approximately 34 hours
|
| gptkbp:metabolism |
liver
|
| gptkbp:side_effect |
dizziness
headache nausea abdominal pain |
| gptkbp:suitable_for |
patients with severe renal impairment
patients taking certain medications that affect liver enzymes patients with congestive heart failure patients with hypersensitivity to azoles |
| gptkbp:type_of |
84625-61-6
|
| gptkbp:used_in |
treatment of aspergillosis
treatment of blastomycosis treatment of cryptococcal meningitis treatment of histoplasmosis treatment of onychomycosis |