Statements (56)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:activities |
inhibits fungal cell membrane synthesis
|
| gptkbp:approves |
gptkb:FDA
|
| gptkbp:availability |
generic version available
|
| gptkbp:brand |
gptkb:itraconazole
|
| gptkbp:class |
triazole antifungal
|
| gptkbp:clinical_trial |
Phase IV
short-term treatment Phase III long-term treatment |
| gptkbp:contraindication |
pregnancy
severe liver disease congestive heart failure lactation concurrent use with certain medications |
| gptkbp:dosage_form |
oral
|
| gptkbp:formulation |
gptkb:beer
oral solution |
| https://www.w3.org/2000/01/rdf-schema#label |
Sporanox
|
| gptkbp:indication |
aspergillosis
onychomycosis histoplasmosis blastomycosis |
| gptkbp:ingredients |
gptkb:itraconazole
|
| gptkbp:interacts_with |
CY P3 A4 inducers
CY P3 A4 inhibitors |
| gptkbp:is_used_for |
treating fungal infections
|
| gptkbp:lifespan |
approximately 34 hours
|
| gptkbp:manager |
oral
|
| gptkbp:manufacturer |
gptkb:Janssen_Pharmaceuticals
|
| gptkbp:marketed_as |
gptkb:legislation
gptkb:United_States gptkb:Native_American_tribe |
| gptkbp:packaging |
gptkb:beer
blister pack |
| gptkbp:products |
gptkb:posaconazole
gptkb:fluconazole voriconazole |
| gptkbp:requires |
prescription only
|
| gptkbp:rounds |
urine
feces |
| gptkbp:scholarships |
avoid alcohol
monitor liver function report any unusual symptoms |
| gptkbp:side_effect |
dizziness
headache nausea abdominal pain heart failure liver toxicity skin rash hypersensitivity reactions elevated liver enzymes |
| gptkbp:storage |
room temperature
|
| gptkbp:bfsParent |
gptkb:itraconazole
|
| gptkbp:bfsLayer |
5
|