|
gptkbp:instanceOf
|
gptkb:protein
cytokine
|
|
gptkbp:associatedWith
|
gptkb:atopic_dermatitis
ulcerative colitis
pulmonary fibrosis
eosinophilic esophagitis
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodedBy
|
gptkb:IL13_gene
|
|
gptkbp:Entrez_Gene_ID
|
3596
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
regulation of immune response
B cell maturation
IgE class switching
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
interleukin-13 protein
|
|
gptkbp:involvedIn
|
allergic inflammation
asthma pathogenesis
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5q31
|
|
gptkbp:modulatedBy
|
fibrosis
macrophage activation
|
|
gptkbp:molecularWeight
|
~13 kDa
|
|
gptkbp:OMIM
|
147683
|
|
gptkbp:PDB
|
1IJZ
|
|
gptkbp:producedBy
|
gptkb:basophils
gptkb:mast_cells
gptkb:T_helper_2_cells
|
|
gptkbp:recipient
|
gptkb:IL-13_receptor_alpha_1
gptkb:IL-13_receptor_alpha_2
|
|
gptkbp:regulates
|
inflammatory response
antigen presentation
mucus production
airway hyperresponsiveness
eosinophil recruitment
fibroblast proliferation
collagen production
chemokine production
epithelial cell function
goblet cell hyperplasia
smooth muscle contractility
|
|
gptkbp:relatedTo
|
interleukin-4 protein
|
|
gptkbp:structure
|
monomeric glycoprotein
|
|
gptkbp:target
|
gptkb:lebrikizumab
gptkb:tralokinumab
monoclonal antibodies
|
|
gptkbp:UniProtID
|
gptkb:P35225
|
|
gptkbp:bfsParent
|
gptkb:IL13
|
|
gptkbp:bfsLayer
|
6
|