inosine-5'-monophosphate dehydrogenase
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:catalyzes |
oxidation of inosine monophosphate to xanthosine monophosphate
|
| gptkbp:cofactor |
NAD+
|
| gptkbp:EC_number |
1.1.1.205
|
| gptkbp:foundIn |
gptkb:Bacteria
eukaryotes |
| gptkbp:gene |
gptkb:IMPDH
|
| https://www.w3.org/2000/01/rdf-schema#label |
inosine-5'-monophosphate dehydrogenase
|
| gptkbp:inhibitedBy |
gptkb:mycophenolic_acid
ribavirin |
| gptkbp:involves |
purine nucleotide biosynthesis
|
| gptkbp:product |
gptkb:H+
gptkb:NADH xanthosine monophosphate |
| gptkbp:requires |
guanosine nucleotide biosynthesis
|
| gptkbp:structure |
homotetramer
|
| gptkbp:substrate |
gptkb:inosine_monophosphate
NAD+ |
| gptkbp:target |
immunosuppressive drugs
|
| gptkbp:UniProtID |
P12268 (human IMPDH2)
P20839 (human IMPDH1) |
| gptkbp:bfsParent |
gptkb:1IC1
|
| gptkbp:bfsLayer |
8
|