immunoreceptor tyrosine-based activation motifs (ITAMs)
GPTKB entity
Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:contains |
tyrosine residues
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:foundIn |
cytoplasmic tails of immune receptors
|
| gptkbp:function |
signal transduction
|
| https://www.w3.org/2000/01/rdf-schema#label |
immunoreceptor tyrosine-based activation motifs (ITAMs)
|
| gptkbp:phosphorylates |
gptkb:protein_tyrosine_kinases
|
| gptkbp:presentIn |
Dectin-1
CD3 chains Fc receptor gamma chain |
| gptkbp:recognizedBy |
SH2 domain-containing proteins
|
| gptkbp:role |
B cell receptor signaling
immune cell activation NK cell activation T cell receptor signaling |
| gptkbp:sequenceConsensus |
YxxL/Ix(6-8)YxxL/I
|
| gptkbp:bfsParent |
gptkb:CD3Z
|
| gptkbp:bfsLayer |
7
|