ζ-chain (CD247)

URI: https://gptkb.org/entity/ζ-chain_(CD247)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:CD3_zeta_chain gptkb:Cluster_of_Differentiation_247
gptkbp:component	gptkb:T-cell_receptor-CD3_complex
gptkbp:contains	gptkb:immunoreceptor_tyrosine-based_activation_motifs_(ITAMs)
gptkbp:discoveredIn	1989
gptkbp:encodedBy	gptkb:CD247_gene
gptkbp:expressedIn	gptkb:human gptkb:mouse right
gptkbp:formsComplexWith	gptkb:CD3_delta_chain gptkb:CD3_epsilon_chain gptkb:CD3_gamma_chain gptkb:T-cell_receptor_alpha_chain gptkb:T-cell_receptor_beta_chain
gptkbp:foundIn	T lymphocytes
gptkbp:function	signal transduction
https://www.w3.org/2000/01/rdf-schema#label	ζ-chain (CD247)
gptkbp:locatedOnChromosome	gptkb:chromosome_1q24.2
gptkbp:location	gptkb:cell_membrane
gptkbp:molecularWeight	16 kDa
gptkbp:mutationAssociatedWith	immunodeficiency
gptkbp:OMIM	186780
gptkbp:requires	T-cell activation
gptkbp:UniProtID	gptkb:P20963
gptkbp:bfsParent	gptkb:T-cell_receptor_complex
gptkbp:bfsLayer	7