|
gptkbp:instanceOf
|
gptkb:antibiotic
carbapenem
|
|
gptkbp:approvedBy
|
gptkb:FDA
1985
|
|
gptkbp:ATCCode
|
gptkb:J01DH51
|
|
gptkbp:brand
|
gptkb:Primaxin
|
|
gptkbp:CASNumber
|
74431-23-5
|
|
gptkbp:combines
|
gptkb:cilastatin
|
|
gptkbp:contraindication
|
hypersensitivity to beta-lactams
|
|
gptkbp:discoveredBy
|
gptkb:Merck_&_Co.
|
|
gptkbp:drugClass
|
gptkb:antibiotic
|
|
gptkbp:effect
|
Gram-negative bacteria
Gram-positive bacteria
|
|
gptkbp:eliminationHalfLife
|
1 hour
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasMolecularFormula
|
C12H17N3O4S
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
imipenem
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits cell wall synthesis
|
|
gptkbp:metabolism
|
gptkb:renal_dehydropeptidase
|
|
gptkbp:notEffectiveAgainst
|
gptkb:methicillin-resistant_Staphylococcus_aureus
gptkb:Enterococcus_faecium
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:routeOfAdministration
|
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
nausea
vomiting
seizures
rash
|
|
gptkbp:spectrumOfActivity
|
broad-spectrum
|
|
gptkbp:usedFor
|
bacterial infections
|
|
gptkbp:bfsParent
|
gptkb:Primaxin
gptkb:Recarbrio
|
|
gptkbp:bfsLayer
|
5
|